Structural Basis for the Mechanochemical Coupling of Kinesin-1 Revealed by Crystal Structural and Biochemical Analyses
نویسندگان
چکیده
منابع مشابه
The structural and mechanochemical cycle of kinesin.
Kinesin is a microtubule-based motor protein that pulls vesicles or organelles towards the plus end of microtubules. Structural changes in the protein that drive motility are coupled to ATP binding and hydrolysis. Here, we attempt to integrate recent structural and kinetic results into a picture of the mechanochemical cycle of kinesin.
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2010
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2009.12.2005